Immune Boosting Ginseng Fucoidan

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Offering Information

Offering Description

FUCOIDAN

BROWN SEAWEED EXTRACT

Scientific research suggests that Fucoidan has the potential for the following health benefits:

• Immunomodulating activity*
• Powerful antioxidant effects*
• Anti-inflammatory activity*
• Beneficial for eczema*
• Beneficial for heart health*
• Beneficial for liver health*
• Beneficial for kidney health*
• Beneficial for bone health*
• Low molecular weight fucoidan for easy absorption*

What is Fucoidan and what does it do?

	Fucoidan is derived from brown algae. It is a sulfated polysaccharide molecule. It has shown a wide range of biological activities in research, including many properties, like anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, and anti-angiogenic.

	Fucoidan can activate the immune system, enhancing the ability of our immune cells to destroy damaged cells.


	Immunomodulatory Activity
	• May regulate immune effects in patients with Chronic hepatitis B virus (HBV) • Stimulate key markers of both innate and specific immunity • Potential role in preventing Mycoplasma pneumoniae infection • Induce cell proliferation and IgM secretion in HB4C5 Cells • Induce cell proliferation and phagocytosis ability in J774.1 Cells • Plays an important role on antioxidant activities

	Anti-Inflammatory Activity
	• Attribute to the down regulation of NF-κB in nucleus • Exhibit anti-inflammatory activity in both oral and topical applications in vivo • Exert prebiotics and anti-inflammatory activities in Caco 2 cells • Positive effect on suppression of eczema and skin inflammatory issues • Change the expression patterns of inflammatory cytokines, which may consequently attenuate RP and RT induced lung fibrosis



	Anti-Tumor Effects ^
	• Inhibit proliferation/metastasis of cancer cells • Inhibit angiogenesis of cancer • Induce apoptosis of cancer cells • Inhibit tumor progression • Inhibit M2 macrophage infiltration in tumor microenvironment, thus increasing anti-tumor immunity • Enhance effects of chemotherapy • Reduce side effects of treatment • Improve cancer cachexia • Inhibit tumor growth or recurrence • Improve Diseases Control Rate (DCR) • Be used as an adjuvant therapy alongside conventional oncology treatments ^ At 4g daily



	Fucoidan on Diabetes
	• Ameliorate pancreatic β-cell death • Ameliorate impaired insulin synthesis via a Sirt-1-dependent manner • Improve hepatic glucose metabolism • Upregulate expression of insulin receptor substrate (IRS)-1, glucose transporter (GLUT), peroxisome proliferator-activated receptor gamma (PPAR), and uncoupling protein (UCP)-1 mRNA in the adipose tissue of diabetic mice • Decrease in urinary sugar and and blood glucose

	Fucoidan on Liver Health
	• Ameliorate effects on the hepatic tissue of db/db mice by increasing hepatic glycogen and antioxidative enzymes • Reduce ALT, exert hepatoprotective in nonalcoholic fatty liver disease (NAFLD) patients • Might be a hepatoprotective supplement for nonalcoholic fatty liver disease NAFLD) patients




	Fucoidan on Kidney Health
	• Prevent renal tubulointerstitial fibrosis by inhibiting the CD44 signal pathway in chronic kidney disease (CKD) model

	Fucoidan on Heart Health
	• Improve cardiac function of aging canine • Improved both the ventricular rhythm and the muscular function of aging subjects • Enhance the cardiac status of mice with PM2.5 exposures by rescued QT interval prolongation, action potential and cardiac hypertrophy, and cardiac fibrosis decline

	Fucoidan on Bone Health
	• Prevent RANKL-Stimulated Osteoclastogenesis • Prevent LPS-Induced Inflammatory Bone Loss via Regulation of Akt /GSK3 β/ PTEN/NFATc1 Signaling Pathway and Calcineurin Activity • Trigger osteogenic differentiation in vitro • Had an anabolic effect on bone mineralization in vivo



	Disclaimer: The information is not a substitute for medical advice, diagnosis, treatment or professional care. Consult a doctor or a qualified healthcare provider with any questions you may have regarding a medical condition.